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产品介绍
Product Description
QIAseq xHYB Custom Human Panels provide a flexible customization, hybrid-capture-based solution to enable sample-to-insight, targeted sequencing of DNA by next-generation sequencing (NGS). QIAGEN’s fast and efficient hybridization capture technology facilitates highly uniform enrichment of target sequences and allows comprehensive variant detection with minimal sequencing effort.
The flexible xHYB workflow allows simultaneous hybridization up to eight indexed whole genome sequencing (WGS) libraries in as little as 30 minutes from as little as 200 ng input per WGS library to yield highly complex libraries.
For customization of enriched targets, QIAGEN offers these options: Fully customized panel: Panel built to target customer’s regions of interest (ROIs) Flexibility to use with existing panel: Panel built to be combined with one of the QIAseq xHYB Human Hybrid Capture Panels or another custom panel Boost existing panel (no limit on the ROI): Panel built to boost ROIs with additional probes for higher coverage
产品特点
Features
- Flexible custom probe design algorithm allows excellent target region coverage
- Highly sensitive detection of variants with low allele frequencies
- Single-day workflow with hybrid capture flexibility ranging from 30 minutes to overnight
- Automation-friendly workflow
产品应用
Applications
QIAseq xHYB Custom Panel may be used in a variety of applications that use targeted sequencing, such as the following:
- Disease-gene identification for rare and inherited disorders
- Population genetics and carrier screening
- Human disease pathways and mechanisms
- Pathogenic infection mechanisms
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