QIAcard FTA DMPK-A (100)，WB129241，Qiagen，凯杰

QIAcard FTA DMPK formats offer a reliable and cost-effective sample collection technique for analyzing pharmacokinetics in clinical studies, global health surveillance programs and forensic applications. Simply apply a small sample of blood or other biofluid directly to the DMPK card and allow it to dry at room temperature – the sample is then stabilized on the card for later use. For downstream analyses, such as HPLC and MS/MS, a small disc can be punched out of the card to extract drugs and metabolites.

• Microvolume sampling requires just 10 to 20 μl per sample
• Detection of harmful byproducts (metabolites), dangerous exposure levels (toxicity) or active substances
• Easy serial sampling from individual animals
• Straightforward extraction for highly consistent data

Drug Metabolism (DM) Pharmacokinetic (PK) studies with sample material derived from blood, plasma, urine, synovial fluid and cerebrospinal fluid analytes. Card choice is dictated by a combination of handling and performance criteria. Handling requirements may be influenced by operational or safety considerations. The overall performance depends on many factors such as the analyte chemical structure, extraction solvent and analysis workflow, which are usually determined empirically.