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产品介绍
Product Description
规格 |
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Accession Number: | NP_004926.1 I NP_003876 |
Assay Entry: | Biochemical phospho-specific activity (no antibody) |
Kinase Group: | Ser⁄Thr Kinases: CMCG Group |
Shipping Condition: | Dry Ice |
Target Entry: | CDK5/p35 |
Expression System: | Baculovirus |
Form: | Frozen |
Protein Form: | Full Length |
Research Category: | Drug Development |
Species: | Human |
Validated Application: | Kinase Assay |
Molecular Weight: | 74.5 kDa |
Gene Alias: | CDK5/p35 |
KinaseFamily: | CDK and CHK Kinase Family |
Protein Tag: | His Tag |
储存 |
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Storage Buffer: 20mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.01% Triton X-100, 2mM DTT, 20% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
描述 |
CDK5 is a cyclin-dependent kinase that plays a critical role in neuron development. The kinase is strongly activated when it complexes with neuron-specific activators, especially p35, but less strongly when it complexes with cyclins. This protein is coexpressed and copurified with p35.
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