规格
Accession Number:	NP_005219.2
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Tyrosine Kinases
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry:	EGFR
Target Gene:	Epidermal growth factor receptor
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Recombinant, Cytoplasmic
Protein Subtype:	Receptor Tyrosine Kinases
Research Category:	Oncology, Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	114294, 1956
Molecular Weight:	90.5 kDa
Gene Alias:	EGFR (ErbB1)
KinaseFamily:	EGF Receptor (ErbB) Kinase Family
Protein Length:	aa 668-1210
Protein Tag:	GST Tag

储存
Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.

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