MAP4K1 (HPK1) 100 ug，PV6356，Invitrogen

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订货号： 9RM0916

品牌型号： Invitrogen PV6356

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最小订货量： 1套

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商品介绍
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产品介绍 Product Description

规格
Kinase Group:	Serine/Threonine Kinase
Species:	Human
Validated Application:	Kinase Assay
Molecular Weight:	65.0 kDa
Gene Alias:	MAP4K1
Protein Length:	aa 1-346
Protein Tag:	GST Tag, His Tag

储存
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.

描述

MAP4K1 (also known as HPK1) or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. MAP4K1 is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway. MAP4K1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76. Recombinant human MAP4K1 (1-346) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

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