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产品介绍
Product Description
规格 |
|
Accession Number: | NP_002735 |
Form: | Frozen |
Kinase Group: | Ser⁄Thr Kinases: AGC Group |
Protein Form: | Full Length |
Research Category: | Drug Development |
Shipping Condition: | Dry Ice |
Species: | Human |
Molecular Weight: | 67.7 kDa |
Gene Alias: | PKC2; PKC-ZETA |
Validated Application: | Kinase Assay |
Expression System: | Baculovirus |
KinaseFamily: | PKC Kinase Family |
Protein Tag: | Untagged |
储存 |
|
Storage Buffer: 20mM HEPES, pH 7.5, 250mM NaCl, 2mM EDTA, 2mM EGTA, 5mM DTT, 0.05% Triton X-100, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
描述 |
The PKC family of serine⁄threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
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