规格
Accession Number:	NP_004374
Assay Entry:	Biochemical binding/kinetic, Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity
Kinase Group:	Tyrosine Kinases
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™
Target Entry:	CSK
Target Gene:	c-src tyrosine kinase
Expression System:	E. coli
Protein Family:	Kinases & Inhibitors
Protein Form:	Full Length, Recombinant, Cytoplasmic
Protein Subtype:	Cytoplasmic Tyrosine Kinases
Research Category:	Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	1445
Molecular Weight:	51.9 kDa
Gene Alias:	CSK
KinaseFamily:	CSK Kinase Family
Protein Tag:	His Tag

储存
Storage Buffer: 50 mM Tris, pH 7.5, 100 mM NaCl, 10% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

CSK is a tyrosine kinase that has been shown to downregulate the activity of SRC oncoprotein through phosphorylation of its carboxy terminus. Since cell transformation by SRC is caused by various mechanisms that interfere with this phosphorylation, the CSK gene might function as an antioncogene.

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