CD31 Antibody, anti-human, Vio® Bright B515, REAfinity™，130-126-884，美天旎

Clone REA730 recognizes the human CD31 antigen, also known as PECAM-1. CD31 is a member of the immunoglobulin superfamily and is involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is a 120–140 kDa single-chain transmembrane glycoprotein expressed on endothelial cells, monocytes, platelets, granulocytes, and several lymphocyte subsets. During maturation of CD4⁺ T cells, the expression of CD31 changes: CD4⁺ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture.

Additional information: Clone REA730 displays negligible binding to Fc receptors.

PECAM-1, EndoCAM, GPIIa, PECA1

Technical specifications