规格
Accession Number:	NP_002735
Kinase Group:	Ser⁄Thr Kinases: AGC Group
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Gene:	protein kinase C, zeta
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Full Length, Recombinant
Protein Subtype:	Serine⁄Threonine Kinases
Research Category:	Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	5584, 5590
Molecular Weight:	67.7 kDa
Gene Alias:	PRKCZ (PKC zeta)
KinaseFamily:	PKC Kinase Family
Protein Tag:	Untagged

储存
Storage Buffer: 20mM HEPES, pH 7.5, 250mM NaCl, 2mM EDTA, 2mM EGTA, 5mM DTT, 0.05% Triton X-100, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

The PKC family of serine⁄threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.

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