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FGFR3 K650E 100 UG,PR8155A,Invitrogen

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订货号 9KM4069
品牌型号 Invitrogen PR8155A
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Accession Number: NP_000133; K650E
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
Expression System: Baculovirus
Form: Frozen
Protein Form: Cytoplasmic
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 49.8 kDa
Gene Alias: FGFR3 K650E
KinaseFamily: FGF Receptor Kinase Family
Protein Tag: His Tag
储存
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
描述

FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. The K650E mutation leads to constitutive activation and the neonatal lethal disorder TDII.

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