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LANTHASCREEN TB-ANTI-P4E-BP1AB 25 UG (KIT),PV4757,Invitrogen

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订货号 9JC8374
品牌型号 Invitrogen PV4757
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Antibody Conjugate: Lanthanide Chelates, Terbium (Tb)
Antibody Molecular Weight: 150000 Da
Assay Entry: Biochemical terbium phospho-specific activity
Excitation/Emission: 340⁄490, 520
Label Type: Lanthanide Chelates
Label or Dye: Tb (Terbium), GFP (EmGFP)
Product Line: LanthaScreen®
Reactivity: Human
Reactivity abrv: Hu
Readout: End Point
Shipping Condition: Dry Ice
Target Entry: mTOR, FRAP1
Target Enzyme: Serine⁄Threonine Kinases
Technique: TR-FRET
Validated Kinases: FRAP1 (mTOR), FRAP1 (mTOR)
Format: 384-well plate
储存
Terbium-labeled anti-4E-BP1 [pThr46] antibody in HEPES buffered saline. Store at -20°C.
描述

A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 upon stimulation of the pathway.

For use in combination with the GFP-4E-BP1 physiological protein substrate (PV4759) to evaluate inhibitors in medium to high throughput screening applications. An optimized mTor assay buffer (PV4794) is also available.

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