Clone REAL1572is an antibody fragment derived from the full S100A4 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.

Clone REAL1572 recognizes S100A4, a member of the large family of S100 protein. S100A4 has long been implicated mainly in tumorigenesis and metastatization and is a key player in promoting pro-inflammatory phenotypes and organ pro-fibrotic pathways. S100A4 is assigned to physiological functions that contribute to neurogenesis, cell motility and chemotaxis, cell differentiation, and cell-cell communication. In addition, extracellular S100A4 is also a potential causation of inflammatory processes and induces the release of cytokines and growth factors under different pathological conditions.

For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

Calvasculin, Metastasin, Placental calcium-binding protein, Protein Mts1, S100 calcium-binding protein A4, CAPL, MTS1, Protein S100-A4

Technical specifications