规格
|
Amino Acid Sequence:
|
Fluorescein-GAGRLGRDKYKTLRQIRQ |
Assay Entry:
|
Biochemical terbium phospho-specific activity |
Detection Method:
|
Fluorescent |
Gene ID (Entrez):
|
120892 |
Label or Dye:
|
FITC (Fluorescein) |
Shipping Condition:
|
Dry Ice |
Substrate:
|
ERM (LRRKtide) |
Substrate Properties:
|
Peptide-Based Substrate |
Target Entry:
|
LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2 |
Target Enzyme:
|
Serine⁄Threonine Kinases |
Validated Kinases:
|
LRRK2 |
Substrate Type:
|
Kinase Substrate |
Molecular Weight:
|
2475.8 Da |
储存
|
400 µM Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C and protect from light. |
A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants.
For use in combination with the LanthaScreen® Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.