规格
Accession Number:	NP_003209.2 ⁄ NP_852664.1
Assay Entry:	Biochemical binding/kinetic, Biochemical ADP accumulation
Kinase Group:	Lipid Kinases
Protein Form:	Full Length, Recombinant
Research Category:	Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	Adapta™
Tag Position:	His (N-Terminal)⁄None
Target Entry:	PIK3CA/PIK3R1
Target Gene:	phosphoinositide-3-kinase, catalytic, alpha polypeptide
Gene ID (Entrez):	5290
Molecular Weight:	128.4⁄83.6 kDa
Protein Subtype:	Lipid Kinases
Gene Alias:	PIK3CA/PIK3R1 (p110 alpha/p85 alpha), PI3 Kinase alpha
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	PI3 Kinase Family
Protein Tag:	His Tag

储存
Storage Buffer: 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.04% Triton X-100, 0.5mM EDTA, 2mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

PIK3CA (p110 alpha) is known to be involved in the PI 3-kinase⁄AKT signaling pathway, which plays an important role in regulating cell growth and apoptosis. PIK3CA is coexpressed and copurified with the regulatory subunit PI3KR1.

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