规格
Accession Number:	NP_004439
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity
Kinase Group:	Tyrosine Kinases
Protein Form:	Recombinant, Cytoplasmic
Research Category:	Oncology, Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™
Target Entry:	ERBB2
Target Gene:	V-erb-b2 erythroblastic leukemia viral oncogene homolog 2
Gene ID (Entrez):	2064
Molecular Weight:	68.6 kDa
Quantity:	10μg
Protein Subtype:	Receptor Tyrosine Kinases
Gene Alias:	ErbB2 (HER2), NEU
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	EGF Receptor (ErbB) Kinase Family
Protein Length:	aa 676-1255
Protein Tag:	His Tag

储存
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.01% CHAPS, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.

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