规格
|
Accession Number:
|
NM_000406.2 |
Assay Entry:
|
Cell-based beta lactamase reporter gene |
Cell Line:
|
CHO-K1 |
Cell State:
|
Dividing Cells |
Druggable Target:
|
GPCRs |
Human Protein Class:
|
G-Protein Coupled Receptor (GPCR) |
Population Status:
|
Single Cell Clone Origin |
Product Line:
|
GeneBLAzer® |
Readout:
|
End Point |
System Type:
|
GeneBLAzer™ |
Target Entry:
|
GnRHR |
Technique:
|
FRET |
Detection Method:
|
Fluorescent |
储存
|
GeneBLAzer® GnRHR-NFAT-bla CHO-K1 cells are shipped on dry ice, 8 x 10^6 cells⁄vial. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. |
GeneBLAzer® GnRHR-NFAT-bla CHO-K1 cells contain the human gonadotropin-releasing hormone receptor (GnRHR), (Accession # NM_001012763) stably integrated into the CellSensor® NFAT-bla HEK 293T cell line. CellSensor® NFAT-bla HEK 293T (Cat No. K1538) cells contain a beta-lactamase reporter gene under control of the NFAT Response Element. GeneBLAzer® GnRHR-NFAT-bla CHO-K1 cells are functionally validated for Z’-factor and EC50 concentrations of Luteinizing Hormone-Releasing Hormone (LH-RH). In addition, GeneBLAzer® GnRHR-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions.