IDH1 Antibody, anti-human, PE, REAdye_lease™，130-130-129，美天旎

Clone REAL1159 is an antibody fragment derived from the full IDH1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.

Clone REAL1159 recognizes the IDH1 enzyme, also known as Isocitrate dehydrogenase (NADP) cytoplasmic, that plays an important role in lipid biosynthesis in different tissues such as the liver, adipose tissues, brain and tumors. Mutations of IDH is related to the progress and prognosis of certain tumors and have been found in numerous cancers, mainly in gliomas, chondrosarcomas or enchondromas, and cholangiocarcinomas. IDH1 is considered to be a specific biomarker for early diagnosis, prognosis and targeted therapy for tumors.

For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDP, Cytosolic NADP-isocitrate dehydrogenase, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, PICD

Technical specifications