规格
|
Accession Number:
|
NP_940980.2 |
Assay Entry:
|
Biochemical terbium phospho-specific activity, Biochemical binding/kinetic |
Kinase Group:
|
Ser⁄Thr Kinases: TKL Group |
Shipping Condition:
|
Dry Ice |
System Compatibility:
|
LanthaScreen®, Adapta™ |
Tag Position:
|
N-Terminal |
Target Entry:
|
LRRK2 R1441C |
Target Gene:
|
LRRK2 R1441C |
Expression System:
|
Baculovirus |
Form:
|
Frozen |
Protein Family:
|
Kinases & Inhibitors |
Protein Form:
|
Catalytic |
Protein Subtype:
|
Serine⁄Threonine Kinases |
Research Category:
|
Signal Transduction, Neurobiology |
Species:
|
Human |
Validated Application:
|
Kinase Assay |
Molecular Weight:
|
205 kDa |
Gene Alias:
|
LRRK2 R1441C |
KinaseFamily:
|
LRRK Kinase Family |
Protein Tag:
|
GST Tag |
储存
|
Kinase proteins are shipped on dry ice and should be stored at -80°C. |
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the R1441C mutation in the GTPase domain.
Related Links:
• LRRK2 tools for advancing Parkinson's disease research
• Kinase protein portfolio
• LanthaScreen® Eu Kinase Binding Assay
• LanthaScreen® Activity Assay