CD158e/k (KIR3DL1/DL2)-PE, human，130-124-439，美天旎

Clone 5.133 reacts with CD158e (KIR3DL1) and CD158k (KIR3DL2), members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of killer immunoglobulin-like receptors (KIR) contributes to the regulation of NK cell-mediated cytotoxicity. Expression is found mainly on CD56^dimCD16⁺ natural killer (NK) cells but also on a subset of CD8⁺ T cells. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs.

KIR3DL1, KIR3DL2

Technical specifications