- 商品介绍
- 规格参数
- 包装参数
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规格 |
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| Accession Number: | NP_000213 |
| Shipping Condition: | Dry Ice |
| Expression System: | Insect |
| Protein Form: | Recombinant, Active, Catalytic, Mutant |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 75.2 kDa |
| KinaseFamily: | PDGFR Kinase Family |
| Protein Length: | aa 544 - end |
| Protein Tag: | GST Tag |
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储存 |
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| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
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描述 |
This KIT V559D V654A recombinant human protein (544–end) was expressed in insect cells. KIT receptor tyrosine kinase is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth. KIT V559D V654A recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔询价
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔询价
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