T Cell TransAct，130-111-160，美天旎

T cell activation via CD3 and CD28 with T Cell TransAct™. This stimulation reagent is ready-to-use for in vitro activation and expansion of human T cells. Its polymeric nanomatrix structure ensures gentle and efficient activation of resting T cells from PBMCs and of enriched T cell populations, while maintaining high viability.

T Cell TransAct™ consists of a colloidal polymeric nanomatrix conjugated to humanized CD3 and CD28 agonists providing primary and co-stimulatory signals for an optimized and efficient T cell activation and expansion. The nanoscale structure of T Cell TransAct™ allows sterile filtration and excess reagent can be removed by centrifugation with following conventional supernatant replacement or simply by medium wash.

Polyclonal T cell expansion can be used when increased numbers of effector cells are required without the use of feeder cells or antigens, or when T cells are activated to enable gene modification.

In vitro stimulation and expansion of T cell populations, either from purified T cells or from PBMCs.