规格
|
Assay Entry:
|
Biochemical ADP accumulation |
Detection Method:
|
Fluorescent |
Gene ID (Entrez):
|
5290, 5294 |
Shipping Condition:
|
Dry Ice |
Substrate:
|
Phosphoinositol-4,5-bisphosphate (PIP2) lipid vesicles with phosphoserine (PS) |
Substrate Properties:
|
Lipid-Based Substrate |
Target Entry:
|
PIK3CG, PIK3CD/PIK3R1, PIK3CA/PIK3R1 |
Target Enzyme:
|
Lipid Kinases |
Validated Kinases:
|
PIK3CA, PIK3CG, PIK3CB, PIK3CD |
Substrate Type:
|
Kinase Substrate |
储存
|
PIP2:PS Lipid Kinase Substrate in 50 mM HEPES pH 7.5, 3 mM MgCl2, and 1 mM EGTA. Store at -20°C. |
Specifically optimized for use with the Class I PI3 kinases (PIK3CA, PIK3CB, PIK3CD, and PIK3CG), this substrate consists of lipid vesicles of a 1:19 molar ratio of phosphoinositol-4,5-bisphosphate (PIP2) with phosphoserine (PS).
For use with the Adapta™ Universal Kinase Assay (PV5099).