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产品介绍
Product Description
规格 |
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Accession Number: | NP_001387 |
Assay Entry: | Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody) |
Kinase Group: | Ser⁄Thr Kinases: CMCG Group |
Shipping Condition: | Dry Ice |
System Compatibility: | Z'-LYTE™ |
Target Entry: | DYRK1A |
Target Gene: | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
Expression System: | Baculovirus |
Protein Family: | Kinases & Inhibitors |
Protein Form: | Full Length, Recombinant |
Protein Subtype: | Serine⁄Threonine Kinases |
Research Category: | Genetic Diseases |
Species: | Human |
Validated Application: | Kinase Assay |
Gene ID (Entrez): | 1859, 2100 |
Molecular Weight: | 113 kDa |
Quantity: | 10μg |
Gene Alias: | DYRK1A, DYRK1 |
KinaseFamily: | DYRK Kinase Family, DYRKs |
Protein Tag: | GST Tag |
储存 |
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Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
描述 |
DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease.
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