规格
Antibody Conjugate:	Lanthanide Chelates, Terbium (Tb)
Antibody Molecular Weight:	150000 Da
Antigen:	Tyrosine kinases
Assay Entry:	Biochemical terbium phospho-specific activity, Cell-based terbium phospho-specific activity (stable)
Excitation/Emission:	340⁄490, 520
Label Type:	Lanthanide Chelates
Label or Dye:	Tb (Terbium), GFP (EmGFP)
Reactivity:	Human
Reactivity abrv:	Hu
Readout:	End Point
Shipping Condition:	Dry Ice
Target Entry:	STAT1, JAK1, JAK2 JH1 JH2, JAK2, TYK2, JAK3, JAK2 JH1 JH2 V617F
Target Enzyme:	Tyrosine Kinases
Technique:	TR-FRET
Validated Kinases:	JAK1, JAK2, JAK3, TYK2
Applications:	Biochemical Kinase Assays
Description:	LanthaScreen™ Tb-anti-pSTAT1 [pTyr701] Antibody Kit, 25μg, Tyrosine Kinases Antigen, Human Species Reactivity, Used For Biochemical Kinase Assays, Drug Discovery and Development, Enzyme and Protein Activity Assays,
Format:	384-well plate
Quantity:	25μg
Regulatory Status:	RUO
Storage Requirements:	–20°C
Type:	Primary
Primary or Secondary:	Primary
Packaging:	1 Kit(s)

储存
Terbium-labeled anti-STAT1 [pTyr701] antibody in HEPES buffered saline. Store at -20°C.

描述

A part of the JAK/STAT Pathway, STAT1 (Signal Transducer and Activator of Transcription 1) is phosphorylated at Tyr701 by the Janus family of tyrosine kinases.

For use in combination with the LanthaScreen® STAT1 U206 cell line (K1469) and the GFP-STAT1 physiological protein substrate (PV5211) to evaluate inhibitors in medium to high throughput screening applications.

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