规格
Accession Number:	NP_001547
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Ser⁄Thr Kinases: Other
Protein Form:	Full Length, Recombinant
Research Category:	Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry:	IKBKB
Target Gene:	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene ID (Entrez):	3551, 4088
Molecular Weight:	114 kDa
Quantity:	10μg
Protein Subtype:	Serine⁄Threonine Kinases
Gene Alias:	IKBKB (IKK Beta)
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	IKK Kinase Family
Protein Tag:	GST Tag

储存
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex.

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