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MLK4 10 UG EA,A30979,Invitrogen

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订货号 7UH9342
品牌型号 Invitrogen A30979
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Accession Number: NP_115811
Protein Form: Recombinant, Active, Catalytic
Shipping Condition: Dry Ice
Molecular Weight: 60.5 kDa
Validated Application: Kinase Assay
Expression System: Insect
KinaseFamily: MAP Kinases
Protein Length: aa 114 - 420
Protein Tag: GST Tag
储存
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
描述

This MLK4 recombinant human protein (114–420) was expressed in insect cells. MLK4 or mixed lineage kinase 4 belongs to the superfamily of MAP kinase kinase kinases (MAP3K1) which contain both ser/thr and tyr kinases activity in their catalytic domains. The structure of this kinase family incorporates an N-terminal Src homology (SH3) domain, followed by the kinase domain, a leucine zipper region, and a CDC42 /RAC -interactive binding (CRIB) motif, but divergent C-terminal regions. MLK4 is highly expressed in kidney and pancreas. MLK4 is a negative regulator of TLR4. MLK4 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

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