PI-16 Antibody, anti-human, APC-Vio® 770, REAfinity™，130-129-855，美天旎

Clone REA699 recognizes the human peptidase inhibitor 16 (PI-16) antigen, also known as CRISP-9 or PSP94-binding protein. PI-16 belongs to the Activity cysteine-rich secretory protein (CRISP) family and is expressed in prostate, testis, ovary, and intestine. It is reported to be an independent prognostic marker for prostate cancer. Additionally, PI-16 is over-expressed by CD4⁺/CD25⁺ Treg cells, so it identifies a novel distinct subset of functional memory Treg cells, that are able to migrate to sites of inflammation and regulate the pro-inflammatory response.

Additional information: Clone REA699 displays negligible binding to Fc receptors.

Peptidase inhibitor 16, CRISP-9, PSP94-binding protein

Technical specifications