规格
|
Product Line:
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Pierce™ |
Crosslinker Type:
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Heterobifunctional |
Labeling Method:
|
Chemical Labeling |
Reactive Moiety:
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Maleimide, Sulfo-NHS Ester |
Solubility:
|
Water |
Spacer:
|
Long |
储存
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Upon receipt store desiccated at 4°C. Product is shipped at ambient temperature. |
Thermo Scientific Pierce Sulfo-KMUS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (16.3 angstroms).
Features of Sulfo-KMUS:
• Reactive groups: sulfo-NHS ester and maleimide
• Reactive toward: amino and sulfhydryl groups
• Long aliphatic spacer arm compared to Sulfo-GMBS
• Sulfo-NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-soluble
Product References:
Crosslinker Application Guide -- search for recent literature references for this product