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CDK13/CYCLIN K 10UG EA,A33510,Invitrogen

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订货号 7LE4690
品牌型号 Invitrogen A33510
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Accession Number: CDK13: NP_003709.3, Cyclin K: NP_001092872.1
Shipping Condition: Dry Ice
Expression System: Insect
Protein Form: Recombinant, Active, Catalytic
Validated Application: Kinase Assay
Molecular Weight: 73.8/63.0 kDa
KinaseFamily: CDKs and CHKs
Protein Length: CDK13: 656 -1050, Cyclin K: 1 - 300
Protein Tag: GST Tag, His Tag
储存
Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol
描述

This CDK13/cyclin K recombinant human protein (CDK13: 656–1050, cyclin K 1–300) was expressed in insect cells. CDK13/cyclin K serine/threonine kinase is dimeric protein complex. CDK13 is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Cyclin K is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain of the large subunit of RNA polymerase II. CDK13/cyclin K recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

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