规格
Accession Number:	NP_004293
Assay Entry:	Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Kinase Group:	Ser⁄Thr Kinases: TKL Group
Protein Form:	Recombinant, Catalytic
Research Category:	Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	Z'-LYTE™
Target Entry:	ACVR1B
Target Gene:	activin A receptor, type IB
Gene ID (Entrez):	3458, 91
Molecular Weight:	68.2 kDa
Protein Subtype:	Serine⁄Threonine Kinases
Gene Alias:	ACVR1B (ALK4)
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	STKR Kinase Family
Protein Length:	aa 150-505
Protein Tag:	GST Tag

储存
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton® X-100, 2 mM DTT, and 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

ACVR1B is a serine⁄threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.

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