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- 规格参数
- 包装参数
产品介绍
Product Description
|
规格 |
|
| Accession Number: | NP_002603.1 |
| Kinase Group: | Ser⁄Thr Kinases: Atypical |
| Mass: | 10 µg |
| Reactivity: | Human |
| Shipping Condition: | Dry Ice |
| System Compatibility: | Adapta™ Universal Kinase Assay |
| Tag Position: | N-Terminal |
| Target Gene: | PDK4 |
| Expression System: | Baculovirus |
| Protein Family: | Kinases & Inhibitors |
| Protein Form: | Full Length, Recombinant |
| Protein Subtype: | Serine⁄Threonine Kinases |
| Research Category: | Signal Transduction |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Gene ID (Entrez): | PDK4 |
| Molecular Weight: | 73.9 kDa |
| Gene Alias: | PDK-4 (PDKH4) |
| Gene Symbol: | PDK4 |
| KinaseFamily: | PDHK Kinase Family |
| Protein Length: | Full-length |
| Protein Tag: | GST Tag |
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储存 |
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|
50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol. Kinase proteins are shipped on dry ice. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhhibition of PDHKs is viewed as a potential therapeutic treament for type II diabetes.
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