CD326 (EpCAM) Antibody, anti-human, PE, REAdye_lease™，130-133-242，美天旎

Clone REAL1555 is an antibody fragment derived from the full CD326 (EpCAM) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.

Clone REAL1555 recognizes the pleiotropic molecule CD326 (EpCAM), which is also known as epithelial cell adhesion molecule (EpCAM). It is involved in cell adhesion, mediates intercellular adhesion and associates with the actin cytoskeleton. The CD326 antigen is an useful diagnostic marker for epithelia and epithelial-derived neoplasm. It is found in metastases, malignant effusions, and cancer stem cells. It is overexpressed in certain carcinomas including colon, pancreas, breast and most adenocarcinomas. CD326 (EpCAM) is not detected on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts. Furthermore, it is suggested, that CD326 could be used as a surface marker for human ESCs.

For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

EGP40, Ep-CAM, KSA, MK-1, TROP1

Technical specifications