规格
Antibody Conjugate:	Lanthanide Chelates, Terbium (Tb)
Antibody Molecular Weight:	150000 Da
Assay Entry:	Biochemical terbium phospho-specific activity
Excitation/Emission:	340⁄490, 520
Label Type:	Lanthanide Chelates
Label or Dye:	Tb (Terbium), FITC (Fluorescein)
Reactivity:	Human
Reactivity abrv:	Hu
Readout:	End Point
Shipping Condition:	Dry Ice
Target Entry:	MAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3
Target Enzyme:	Serine⁄Threonine Kinases
Technique:	TR-FRET
Validated Kinases:	BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Applications:	Biochemical Kinase Assays
Conjugate:	FITC (Fluorescein), Tb (Terbium), lanthanide chelates
Format:	384-well plate
Gene Alias:	COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, CRAF,NS5,Raf-1,c-Ra, MEKK9,MLK1,PRKE, COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, MEKK7,TAK1,TGF1, MEKK9,MLK1,PRKE, ASK1,MAPKKK5,MEKK, MEKK10,MLK2,MS, MEKK11,MGC17114,MLK-3,MLK3,PTK1,SPR, CRAF,NS5,Raf-1,c-Ra,
Molecular Weight of Antigen:	150kDa
Quantity:	25μg
Regulatory Status:	RUO
Storage Requirements:	–20°C
Type:	Primary
Primary or Secondary:	Primary
Gene ID (Entrez):	10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Packaging:	1 Kit(s)
Includes:	0.02% Sodium azide

储存
Terbium-labeled anti-MAP2K1 [pSer217/221] antibody in HEPES buffered saline. Store at -20°C.

描述

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate inhibitors in medium to high throughput screening applications.

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