CD277 Antibody, anti-human, APC，130-124-880，美天旎

Clone BT3.1 recognizes the human CD277 antigen, a single-pass type I membrane protein, which is also known as butyrophilin subfamily 3 member A1 (BTN3A1). CD277 belongs to the B7 family members and is expressed in various immune cells such as T cells, B cells, monocytes, NK cells, dendritic cells, a subset of stem cells, and endothelial cells. It is also consistently expressed in stromal and some tumor cells. CD277 triggering considerably enhances T cell receptor (TCR) induced cytokine production and cell proliferation. It mediates the response of T cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

BTN3A1, BTF5, BT3.1, BTN3.1, BTN3A2, BT3.2, BTF4, BTN3.2

Technical specifications