CD127-APC, mouse, REA680, 100 tests，130-122-938，美天旎

Clone REA680 recognizes the mouse antigen CD127, also known as IL-7 receptor α chain (IL-7Rα). Mouse CD127 is a 60–90 kDa type I transmembrane glycoprotein. It is a component of the high affinity IL-7 receptor (IL-7R) and the receptor for thymic stromal lymphopoietin (TSLP). CD127 is expressed on immature B cells, CD4^-CD8^-, CD4⁺, and CD8⁺ thymocytes, naive and memory T cells, thymic NK cells, and bone marrow stromal cells. Upon activation of naive T cells, CD127 expression is downregulated. Re-expression of CD127 identifies the effector cells that will differentiate into memory T cells.

Additional information: Clone REA680 displays negligible binding to Fc receptors.

IL-7R, IL-7Rα, IL-7Ralpha

Technical specifications