- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
|
规格 |
|
| Antibody Conjugate: | Lanthanide Chelates, Terbium (Tb) |
| Antibody Molecular Weight: | 150000 Da |
| Assay Entry: | Biochemical terbium phospho-specific activity |
| Excitation/Emission: | 340⁄490, 520 |
| Label Type: | Lanthanide Chelates |
| Label or Dye: | Tb (Terbium), FITC (Fluorescein) |
| Product Line: | LanthaScreen® |
| Reactivity: | Human |
| Reactivity abrv: | Hu |
| Readout: | End Point |
| Shipping Condition: | Dry Ice |
| Target Entry: | LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2 |
| Target Enzyme: | Serine⁄Threonine Kinases |
| Technique: | TR-FRET |
| Validated Kinases: | LRRK2 |
| Format: | 384-well plate |
| Gene ID (Entrez): | 120892 |
|
储存 |
|
| Terbium-labeled anti-ERM [pLRRKtide] antibody in HEPES buffered saline. Store at -20°C. |
|
描述 |
A phospho specific antibody directed to the ezrin/radixin/moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease.
For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
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