规格
Accession Number:	NP_004926.1 I NP_003876
Assay Entry:	Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Kinase Group:	Ser⁄Thr Kinases: CMCG Group
Shipping Condition:	Dry Ice
System Compatibility:	Z'-LYTE™
Target Entry:	CDK5
Target Gene:	cyclin-dependent kinase 5
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Full Length, Recombinant
Protein Subtype:	Serine⁄Threonine Kinases
Research Category:	Cell Cycle & Proliferation, Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Molecular Weight:	36.7⁄51.0 kDa
Gene Alias:	CDK5/p25, CDK5R
KinaseFamily:	CDK and CHK Kinase Family
Protein Tag:	GST Tag, His Tag

储存
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

CDK5 plays a critical role in neuron development. The disregulation of the CDK5 and the truncated activator p25 is believed to be involved in neurodegenerative diseases such as Alzheimer's, Parkinson's, and Amyotrophic Lateral Sclerosis. This protein is coexpressed and copurified with p25.

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