规格
|
Antibody Conjugate:
|
Lanthanide Chelates, Terbium (Tb) |
Antibody Molecular Weight:
|
150000 Da |
Antigen:
|
Tyrosine kinases |
Excitation/Emission:
|
340⁄490, 520 |
Label Type:
|
Lanthanide Chelates |
Label or Dye:
|
Tb (Terbium), GFP (EmGFP) |
Reactivity:
|
Human |
Reactivity abrv:
|
Hu |
Readout:
|
End Point |
Shipping Condition:
|
Dry Ice |
Target Enzyme:
|
Tyrosine Kinases |
Technique:
|
TR-FRET |
Validated Kinases:
|
JAK1, JAK2, JAK3, TYK2 |
Applications:
|
Biochemical Kinase Assays |
Concentration:
|
0.45mg/mL |
Conjugate:
|
GFP (EmGFP), Tb (Terbium), lanthanide chelates |
Format:
|
384-well plate |
Molecular Weight of Antigen:
|
150kDa |
Quantity:
|
1mg |
Regulatory Status:
|
RUO |
Storage Requirements:
|
–20°C |
Type:
|
Primary |
Primary or Secondary:
|
Primary |
Packaging:
|
1 Kit(s) |
储存
|
Terbium-labeled anti-STAT1 [pTyr701] antibody in HEPES buffered saline. Store at -20°C. |
A part of the JAK/STAT Pathway, STAT1 (Signal Transducer and Activator of Transcription 1) is phosphorylated at Tyr701 by the Janus family of tyrosine kinases.
For use in combination with the LanthaScreen® STAT1 U206 cell line (K1469) and the GFP-STAT1 physiological protein substrate (PV5211) to evaluate inhibitors in medium to high throughput screening applications.