规格
|
Accession Number:
|
NM_000868.1 |
Assay Entry:
|
Cell-based beta lactamase reporter gene |
Cell Line:
|
CHO-K1 |
Cell State:
|
Dividing Cells |
Druggable Target:
|
GPCRs |
Human Protein Class:
|
G-Protein Coupled Receptor (GPCR) |
Population Status:
|
Single Cell Clone Origin |
Product Line:
|
GeneBLAzer® |
Readout:
|
End Point |
Reporter Gene:
|
BLA (Beta-Lactamase) |
System Type:
|
GeneBLAzer™ |
Target Entry:
|
HTR2C |
Technique:
|
FRET |
Detection Method:
|
Fluorescent |
储存
|
GeneBLAzer® cell lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. |
GeneBLAzer® HTR2C-NFAT-bla CHO-K1 cells contain the human 5-hydroxytrptamine (serotonin) receptor 2C (HTR2C), (Accession #NM_000868.1) stably integrated into the CellSensor® NFAT-bla CHO-K1 cell line. CellSensor® NFAT-bla CHO-K1 cells (Cat. no.K1078) contain a beta-lactamase reporter gene under control of the NFAT Response Element. The GeneBLAzer® HTR2C-NFAT-bla CHO-K1 cells are functionally validated for Z’-factor and EC50 concentrations of 5-Hydroxytrptamine. In addition, GeneBLAzer® HTR2C-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions.