规格
Accession Number:	NM_004248.2
Assay Entry:	Cell-based beta lactamase reporter gene
Cell Line:	CHO-K1
Cell State:	Dividing Cells
Druggable Target:	GPCRs
Gene Symbol:	GPR10
Population Status:	Single Cell Clone Origin
Product Line:	GeneBLAzer®
Reporter Gene:	BLA (Beta-Lactamase)
System Type:	GeneBLAzer™
Target Entry:	GPR10
Technique:	FRET
Detection Method:	Fluorescent

储存

Contents:
K1732 GeneBLAzer® GPR10 CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® GPR10 CRE-bla CHO-K1 cells
• GeneBLAzer® GPR10 CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer® GPR10 CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

描述

GeneBLAzer® GPR10 CRE-bla CHO-K1 cells contain the human Prolactin Releasing Peptide (GPR10) stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer® GPR10 CRE-bla CHO-K1 cells are functionally validated for Z' and EC₅₀ concentrations of PrRP20. In addition, GeneBLAzer® GPR10 CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The GPR10 receptor has been implicated in a variety of metabolic disorders, including lactation, the regulation of food intake, and other physiological functions.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

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