- 商品介绍
- 规格参数
- 包装参数
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规格 |
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| Crosslinker Type: | Heterobifunctional |
| Labeling Method: | Chemical Labeling |
| Product Line: | Pierce™ |
| Reactive Moiety: | Haloacetyl, NHS Ester |
| Spacer: | Short |
| Solubility: | DMSO (Dimethylsulfoxide), DMF (Dimethylformamide) |
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储存 |
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| Upon receipt store at 4°C protected from moisture. Product is shipped at ambient temperature. |
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描述 |
Thermo Scientific Pierce SIA is a very short (1.5 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
Features of SIA:
• Reactive groups: NHS ester and iodoacetyl
• Reactive toward: amino and sulfhydryl groups
• Shortest sulfhydryl-reactive and amine-reactive heterobifunctional crosslinker available; compare to SIAB
• NHS ester reacts with primary amines at pH 7-9 to form a stable amide bond
• Iodoacetyl group reacts with sulfhydryl groups at pH > 7.5 to form stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
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¥ 55311.07
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¥ 1553.00
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