CD45 Antibody, anti-human, Vio® B515, REAdye_lease™，130-133-244，美天旎

Clone REAL1556 is an antibody fragment derived from the full CD45 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.

Clone REAL1556 recognizes the human CD45 antigen, a member of the protein tyrosine phosphatase (PTP) family also known as the leukocyte common antigen (LCA). The CD45 molecule, a type I transmembrane protein, is required for T and B cell activation and involved in cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 is expressed in different isoforms (CD45RA, CD45RB, CD45RC, CD45RAB, CD45RAC, CD45RBC, CD45RO, CD45R (ABC)) depending on the differentiation status of the cell. REAL1556 recognizes a common epitope of all CD45 isoforms.

For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Ptprc, GP180, L-CA, LY5, T200, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen

Technical specifications