规格
Accession Number:	NP_002604
Assay Entry:	Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Kinase Group:	Ser⁄Thr Kinases: Atypical
Protein Form:	Full Length, Recombinant
Research Category:	Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	Zin-LYTE™, Omnia® Bulk Substrate
Target Entry:	PDK1
Target Gene:	3-phosphoinositide dependent kinase-1
Gene ID (Entrez):	5163, 5170
Molecular Weight:	66.9 kDa
Protein Subtype:	Serine⁄Threonine Kinases
Gene Alias:	PDK-1
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	PDHK Kinase Family
Protein Tag:	His Tag

储存
Storage Buffer: 50mM Tris, pH 7.5, 100mM NaCl, 0.5mM EGTA, 0.5mM EDTA, 0.05% Triton X-100, 5mM DTT, 20% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

PDK1 (3-phosphoinositide dependent kinase-1) is a serine⁄threonine protein kinase localized to the plasma membrane. It plays a vital role in insulin-induced glycogen synthesis, PKC activation, and activation of the AGC subfamily of protein kinases.

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