CD197 (CCR7) Antibody, anti-mouse, APC, REAfinity™，130-126-307，美天旎

Clone REA685 recognizes the mouse CD197 (CCR7) antigen, a chemokine receptor for chemokines CCL19 and CCL21. CD197, like other chemokine receptors has seven transmembrane spanning domains and signals via G proteins. Expression of CD197 is found on semi-mature and mature dendritic cells (DCs), naive B and T cells, regulatory T (Treg) cells, a subpopulation of T cells called central memory T cells, and non-immune malignant cells. CD197 is involved in regulating homing of immune cells, immunity to pathogens, immune tolerance, development and function of Tregs, and manifestation of autoimmunity.

Additional information: Clone REA685 displays negligible binding to Fc receptors.

C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, EBI1, MIP-3 beta receptor, EBI-1

Technical specifications