- 商品介绍
- 规格参数
- 包装参数
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规格 |
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| Product Line: | Pierce™ |
| Crosslinker Type: | Heterobifunctional |
| Labeling Method: | Chemical Labeling |
| Reactive Moiety: | NHS Ester, Pyridyldisulfide |
| Solubility: | DMSO (Dimethylsulfoxide), DMF (Dimethylformamide) |
| Spacer: | Cleavable, Mid-Length |
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储存 |
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| Upon receipt store desiccated at -20°C. Product is shipped at ambient temperature. |
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描述 |
Thermo Scientific Pierce SMPT is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form strong (hindered) yet cleavable (reducible) disulfide bonds with cysteine sulfhydryls.
Features of SMPT:
• Reactive groups: NHS ester and pyridyldithiol
• Reactive towards: amino and sulfhydryl groups
• Cleavable with disulfide reducing agents
• Water-insoluble (dissolve first in DMF or DMSO)
• Contains a hindered disulfide bond; has formed immunotoxins with improved stability
• In vitro, an SMPT conjugate was as effective as conjugates formed with SPDP and 2-IT
• Compare to other varieties of SPDP-type reagents, including pegylated forms
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
SPDP (succinimidyl 3-(2-pyridyldithio)propionate)
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