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The REAlease CD8a MicroBead Kit, mouse has been developed for positive selection of mouse CD8a+ cells from single-cell suspensions of lymphoid and non-lymphoid tissues by using MS or LS columns for manual isolations and autoMACS Columns on the autoMACS NEO Separator for automated solutions. The CD8a antigen is expressed on most thymocytes, almost all cytotoxic T cells and on subpopulations of dendritic cells. CD8a functions as an accessory molecule in the recognition of MHC class I/peptide complexes by the TCR heterodimer on cytotoxic CD8a+ T cells.
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