MACS^® GMP CD25 Fluorescent Antibodies consist of a mouse monoclonal antibody against the human CD25 antigen conjugated to a fluorochrome. They are developed for flow cytometric identification and flow cytometric sorting of CD25 positive cells.

MACS GMP CD25-PE-Biotin can further more be used for a magnetic pre-enrichment step using the CliniMACS^® Anti-Biotin Product Line.

Alternative names

IL-2Rα, p55, Tac

Technical specifications

Background information

The CD25 antibody (clone 3G10) recognizes a 55 kDa glycoprotein also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). This molecule reveals three epitope regions: A, B, and C. Clone 3G10 recognizes epitope region A.

The CD25 antigen is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4-positive regulatory T cells.

Applications

MACS GMP CD25 Fluorescent Antibodies are for identification of CD25 positive cells by flow cytometry as well as cell enrichment by flow cytometric sorting. MACS GMP CD25-PE-Biotin can furthermore be used for a magnetic pre-enrichment step using the CliniMACS Anti-Bioin Product Line.

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Disclaimer

MACS GMP Products are for ex vivo cell processing only, and are not intended for human in vivo applications. For regulatory status in the USA, please contact your local representative.

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