规格
Accession Number:	NP_006197, T674T
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Tyrosine Kinases
Protein Form:	Recombinant, Cytoplasmic
Research Category:	Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Entry:	PDGFRA T674I
Target Gene:	platelet-derived growth factor receptor, alpha polypeptide
Gene ID (Entrez):	5156
Molecular Weight:	89.8 kDa
Protein Subtype:	Receptor Tyrosine Kinases
Gene Alias:	PDGFRA T674I, PDGFR alpha
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	PDGFR Kinase Family
Protein Length:	aa 550-1089; T674I
Protein Tag:	GST Tag

储存
Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA T674I is a Gleevec resistant form of PDGFRA.

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