规格
Accession Number:	NP_075261
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Tyrosine Kinases
Protein Form:	Recombinant, Cytoplasmic
Research Category:	Oncology, Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Entry:	FGFR2
Target Gene:	fibroblast growth factor receptor 2
Gene ID (Entrez):	2263
Molecular Weight:	52.1 kDa
Protein Subtype:	Receptor Tyrosine Kinases
Gene Alias:	FGFR2, CEK3, TY14, BEK
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	FGF Receptor Kinase Family
Protein Length:	aa 403-822
Protein Tag:	His Tag

储存
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.04% Triton X-100, 4mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy.

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