CD13 Antibody, anti-human, Vio® Bright B515, REAfinity™，130-125-612，美天旎

Clone REA1254 recognizes the CD13 antigen, a 150–170 kDa type II transmembrane glycoprotein, which is also known as aminopeptidase N or gp150. CD13 is expressed on granulocytes, myeloid progenitors, endothelial cells, epithelial cells, and subset of granular lymphoid cells. It is also broadly expressed in other tissues such as kidney proximal tubules, intestine, and placenta. CD13 is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It also serves as a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in CD13 appear to be a cause of various types of leukemia or lymphoma.

Additional information: Clone REA1254 displays negligible binding to Fc receptors.

ANPEP, APN, gp150, LAP1, p150, PEPN

Technical specifications